Text Size :

Major Depressive Disorder

Once a person experiences one Major Depressive Episode, they are considered to have a Major Depressive Disorder.  This is because after a first episode there is an 85% chance that a person will have another episode within the next 15 years [ref].  In other words, most people with Major Depressive Disorder experience multiple Major Depressive Episodes in their lifetime.

If a person with a Major Depressive Disorder experiences a Manic or Mixed Episode even once in their life, and this episode was not directly caused by a drug (including an antidepressant) or a general medical condition, then the person's diagnosis automatically changes to Bipolar I Disorder.  If the person experiences even one Hypomanic Episode that was not directly caused by a drug or general medical condition, then their diagnosis changes to Bipolar II Disorder.



Major Depressive Episode